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MD Anderson Cancer Center Postdoctoral Fellow in Houston, Texas

The Kalluri laboratory at the MD Anderson Cancer Center wants to expand its work on the molecular underpinnings of cancer initiation, progression, and metastasis, and to translate the findings into novel therapeutic approaches. The Kalluri laboratory focuses on innovative research in the area of cancer biology with a specific focus on oncogene addiction, tumor microenvironment, stromal biology, exosome biology, tumor metabolism, and tumor immunology. Recent publications on the stromal biology of cancer (Ozdermir et al. 2014, Cancer Cell), exosomes biology in cancer (Kalluri & LeBleu, 2020, Science, Melo et al., 2014 Cancer Cell; Melo et al. 2015, Nature), tumor immunology (Ozdermir et al. 2014, Cancer Cell; Carstens et al. 2017, Nature Communications), metastasis (Zheng et al. 2015, Nature; Lovisa et al. 2015, Nature Medicine), exosomes mediated oncogene targeting (Kamerkar et al. 2017, Nature) and tumor metabolism (LeBleu et al. 2014, Nature Cell Biology, Becker et al. 2020, Cell Reports), have formed the framework for the next set of projects that use innovative technologies such as CRISPR-Cas9, single cell and nuclei sequencing, exosome engineering and mouse modeling to address cutting-edge questions in cancer biology. The Kalluri laboratory strives to transform seminal basic cancer research to inform clinical translation of such findings and will employ any required technology to address important unanswered questions in cancer biology. With strong funding from the NCI, CPRIT Established Investigator Award, and other funding sources, the laboratory is well positioned to exploit the new avenues for fundamental discoveries in cancer and translate such findings into the clinic, exploiting the translational potential of MD Anderson Cancer Center.

LEARNING OBJECTIVES

We seek outstanding candidates with a strong background in immunology. We are only interested in scientists who are committed to solving important questions in cancer biology and are innovative and `out of the box in their approach to science. The candidate must demonstrate expertise in immunology, and interests in exosome biology, tumor biology, tumor microenvironment, mouse modeling of disease, and advancing therapeutic testing. The ideal candidate must demonstrate a committed enthusiasm for science, superior interpersonal and communication skills, exceptional organization skills, and the ability to work in dynamic teams.

ELIGIBILITY REQUIREMENTS

Applicants must have a recent Ph.D. degree with strong research interests.

ADDITIONAL APPLICATION INFORMATION

A cover letter is required and uploaded with a CV. Areas of research interest must highlight publication records and list future professional aspirations. A minimum of 3 reference letters are required.

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